Tuesday, March 29, 2011

H1N1 Case in Austin

Below the case of H1N1 in Austin.

Concerns over H1N1 haven't been talked about in the news lately.

But at Seton they are still seeing cases come in and in some instances it's so severe it's life threatening.

"I was sick - I was so sick," said Cynthia Short.

When Cynthia Short was 35 weeks pregnant she became very sick.

"I was tried and drained and I couldn't get out of bed it was awful," said Short.

She knew this sickness wasn't baby related.

Her doctor said it was allergies but when she went into the emergency room she was admitted immediately.

"We were terrified," said Bill Short, Cynthia's husband.

Cynthia's heart rate was elevated and doctors couldn't figure out why she couldn't breathe.

After an emergency c-section her condition didn't improve so she was transferred to Seton.

Doctors gave a grim outlook.

"She is really in critical condition and there is only one other alternative to what we tried thus far," said Bill Short.

That was a new machine called ECMO.

"We enabled her lungs to rest and get through the disease process," said Dennis Biggan, Perusionist at Seton.

For 17 days Cynthia was mostly unconscious as the machine took her blood out of her body before it reached her heart, pumped it with oxygen, and put it back in so she was able to survive.

"Her lungs were so sick they couldn't transfer that oxygen into the blood or take that carbon dioxide out of the blood," said Biggan.

That sickness turned out to be H1N1.

"H1N1 is still a problem so we know we've heard of a rise of it in the past and it's still present today," said Erin August, Adult ECMO Coordinator.

This year alone three adults between the ages of 29 and 49 have spent weeks on ECMO in order to live.

"It's not the population we would think would be most at risk," said August.

Turns out Cynthia never got her flu shot.

Monday, March 21, 2011

H1N1 Influenza Reappears in Venezuela

Below another case of virus H1N1.

Venezuelan government reported on Friday the death of a patient with H1N1.

State health director Gustavo Miranda Villasmil confirm the death of a patient who came from the town of Cua, adding that four others of the same family were infected.

Eight other people were infected in the country.

Venezuelan Health Minister Maria Eugenia Sader said that the official media on Friday that the government is preparing to fight against a new outbreak of this disease.

Friday, March 18, 2011

Stop The H1N1 Spread

Here's about stop the H1N1 spread.

Influenza virus infection, which is sometimes called the "flu", is a highly contagious viral infection that causes general symptoms such as fever, headache and muscle pain, nasal congestion, sore throat, runny nose and cough.

In the past, people living in tropical and subtropical countries, influenza is a problem only in Western countries with colder climates.

However, influenza surveillance systems in Malaysia and neighboring countries consistently show that the flu is an important cause of disease in children. Since 1997, when the deadly strain of bird flu is usually (H5N1) occurred in the East Asian governments have been improved and enhanced influenza surveillance.

In addition to identifying new viral strains, a serious global pandemic, such outbreaks can cause unknown, they provide valuable information on influenza surveillance systems have been given, and during what time of year, most of the infections.

Malaysia, influenza infections all year round with peak times between May and June and August and September.

This knowledge will help meet public health leaders, and doctors make better decisions, both to avoid the flu vaccine, and influenza virus infection, some children who are at high risk for serious complications from the treatment.

Understanding the basics

The widespread belief that influenza is neither common nor severe is something that has to change. Influenza viruses constantly circulate around the world, causing millions of illnesses, and significant economic losses, mainly in terms of missed work and school days and millions of clinic visits.

At unpredictable intervals, a new strain of influenza virus may emerge, to which most people have no immunity. This leads to a global epidemic known as a pandemic.

This is what happened in 2009 when the H1N1 influenza virus emerged. As of August 2010, more than 214 countries have been affected by the H1N1 pandemic influenza strain, with over 18,449 reported deaths. In Malaysia alone, up to May 2010, there have been 14,772 confirmed H1N1 cases, with 87 deaths.

Good hygiene practices such as frequent hand washing, covering one's mouth when sneezing and coughing, and staying home when feeling ill, can help to reduce the spread of influenza. In reality however, these behaviours are difficult to consistently practise, especially with children and in crowded conditions.

By far, the most effective method to prevent influenza infection is annual vaccination.

Thursday, March 17, 2011

30 provinces report A/H1N1 flu patients

Today about H1N1 cases.

The medical watchdog warns that schools, residential areas and crowded places are the most vulnerable to the epidemic’s outbreak.

Tao Van San, Director of the Health Centre of Muong Nhe district, Dien Bien province, said that 91 cases of the disease were detected in the district’s boarding school from February 14-22. The provincial health sector took preventive measures to successfully contain the disease and pupils have resumed studies at school.

At a junior high school in Quy Nhon city, Binh Dinh province, five pupils tested positive for the epidemic. Previously, 28 pupils from the school showed A/H1N1 symptoms such as fever, sneezing and having runny nose.

In the face of an A/H1N1 outbreak, the Health Ministry warns that cold, humid weather is favourable for the development and contagion of A/H1N1 virus. Offices, schools and factories are recommended to closely monitor the health of workers and students to proactively curb the spread of the disease.

Wednesday, March 16, 2011

Definition of Infected (H1N1)

Below about definition of H1N1.

Suspect Case

Defined as an individual with an acute febrile respiratory illness (fever >38°C) with onset of symptoms:

* Within 7 days of travel to affected areas; or
* Within 7 days of close contact with a confirmed or probable case of Influenza A (H1N1)

Probable Case

Defined as an individual with an acute febrile respiratory illness (fever >38°C) with an influenza test that is positive for Influenza A but is un-subtypeable by reagents used to detect seasonal influenza virus infection, OR;

An individual with a clinically compatible illness or who died of an unexplained acute respiratory illness who is considered to be epidemiologically linked to a probable or a confirmed case.
Confirmed Case

Defined as an individual with laboratory confirmed Influenza A (H1N1) virus infection by one or more of the following tests:

* Real-time RT-PCR;
* Viral culture;
* Four-fold rise in Influenza A (H1N1) virus specific neutralising antibodies.

Monday, March 14, 2011

One More H1N1 Victim Reported in Vietnam

Today's article about H1N1 cases.

The Center for Preventive Medicine in the central province of Quang Nam has confirmed the death of 47 Do Van Tuong Tam Ky Town deadly H1N1 virus. This is the first death in the Central Province.

Tuong was admitted to the General Hospital on Feb. 22 with symptoms of fever and respiratory failure. When his condition worsened, he was transferred for further processing in a large hospital in Da Nang. However, all efforts by doctors have not been successful because his condition worsened. He died four days later.

The doctors at the Center for Preventive Medicine has helped her parents in the conduct of funeral procedures in accordance with the rules. They also took blood samples from relatives and all doctors who have had contact with him in the general hospital. Test results showed that the wife and daughter were H1N1 positive cases. They were immediately quarantined.

Sunday, March 13, 2011

H1N1 Influenza Virus has Spread to 30 Provinces and Cities

These about H1N1 influenza virus has spread.

Dr Nguyen Van Binh, head of the Preventive Medicine Department announced on Friday that most of the deaths were of people already being treated for diabetes, high blood pressure and lung congestion.

Health workers have just conducted tests for the A/H1N1 virus in some localities. As a result, there is no substantial number of people infected with the disease.

According to Dr Binh, people must wear mufflers when they have symptoms like cold, cough or a running nose and immediately go to health clinics for a check up, to deter the timely effects of the A/H1N1 virus.

Organizations, companies and schools should monitor their staff and students’ health to prevent the influenza from spreading.

According to the World Health Organization, the swine flu has come into the post-epidemic phase. Over the last several months, the A/H1N1 virus has been uncovered in 64 countries around the world.

Friday, March 11, 2011

Officials wary of H1N1will come

Below abot H1N1.

H1N1 is a major problem in 2009, and health officials warn that people should not assume that it is the story.

"Historically, there are at least two or three waves of flu," Brown County Health Department Director Judy Friederichs said Tuesday. "We've had two: one in the spring and one in the fall. There's still that potential that we could have the third wave, so we're trying to stay ahead of it."

Friederichs and public health officials made ​​vaccination clinic Tuesday at the Lambeau Field Atrium, where several hundred local residents turned out. Who should not have been vaccinated, he said.

"I certainly think there are still quite a few people who need to be immunized," Friederichs said. Her department will sponsor two more clinics next week, with the times and sites announced later this week.

"We certainly don't want to repeat the fall," she said.

The Wisconsin Department of Health Services is asking public health departments to increase efforts to reach minority communities. State data showed that a higher ratio of minorities were hospitalized with H1N1 during the fall outbreak than nonminorities.

State officials said there were several possible reasons for the disparity, including reduced access to health care for minorities.

Friederichs said reaching minority and diverse populations has been a priority.

"We've tried to focus outreach on those weeks when we've had clinics," Friederichs said, saying 400 to 500 fliers were distributed in targeted areas. The fliers had both English and Spanish translations, urging people to be immunized.

Thursday, March 10, 2011

Cautious With H1N1 Virus

Today's about being cautious with virus H1N1.

In the fall of 1917, a new strain of influenza in circles around the world. At first, the typical flu-like wabak: Sebahagian great force of death among the elderly, while young people recover quickly. However, in the summer of 1918, the version of the deadly virus that has broken out, with disastrous consequences. In total, the pandemic has killed at least 50 million people - about 3 peratus than the world population at that time.

Such unlicensed two waves is typical of the pandemic influenza virus, which is why many scientists are reluctant influenza virus H1N1 in 2009 without a license (the "pig") can be transformed into a deadly form.

H1N1 has been reported on a Mac 2009 in Mexico, contain the right mix of human and pig genes of avian influenza, which encourages doubt that free can be deadlier than a typical flu season. However, the death toll is much lower than dikhuatiri, virus turned into a great Keran sebahagian cekap relatively spread from person to person.

In a new MIT study, the researchers mengenalpasti single genetic mutation of the H1N1 virus that allow you to be much more easily contagious among humans. The discovery, reported in the second edition of the journal Mac Public Library of Science (PLoS) One, it must provide Pertubuhan Kesihatan World, which traces the evolution of influenza, something to watch, "says Ram Sasisekharan, senior author of the paper.

“There is a constant need to monitor the evolution of these viruses,” says Sasisekharan, the Edward Hood Taplin Professor and director of the Harvard-MIT Division of Health Sciences and Technology. Some new H1N1 strains have already emerged, and the key question, Sasisekharan adds, is whether those strains will have greater ability to infect humans.

WHO labs around the world are collecting samples of human and avian flu strains, whose DNA is sequenced and analyzed for potential significant mutations. However, it’s difficult, with current technology, to predict how a particular DNA sequence change will alter the structure of influenza proteins, including hemagglutinin (HA), which binds to receptors displayed by cells in the human respiratory tract. Now that this specific HA mutation has been identified as a potentially dangerous one, the WHO should be able to immediately flag any viruses with that mutation, if they appear.

Identifying this mutation is an important step because it is usually very difficult to identify which of the many possible mutations of the HA protein will have any impact on human health, says Qinghua Wang, assistant professor of biochemistry at Baylor College of Medicine. “These are exactly the types of mutations that we need to watch out for in order to safeguard humans from future disastrous flu pandemics,” he says.

Any ideas or comment just leave it below.

Wednesday, March 9, 2011

H1N1 : HCMC Resident Dies

These about H1N1 cases.

The 52 year old man was under treatment for fever and cough for the last few days but his condition was not showing any signs of improving. He was moved to the Tropical Diseases Hospital on February 28, as his condition deteriorated with pneumonia and respiratory problems.

Tests proved that he was positive for H1N1 virus. Medical workers tried to save him by giving antibiotics and Tamiflu, but their efforts proved futile and his condition worsened. He died after a day of treatment.

Medics have warned residents not to neglect any case of simple fever or cough as the epidemic conditions for H1N1 virus were prevalent in the city. People must immediately visit nearby medical clinics when they experienced fever and cough.

Source

Please leaves your comment if you have any ideas.

Tuesday, March 8, 2011

Companies Plan for Mass Flu Absences

Below about H1N1.

The spread of the H1N1 virus has larger employers adapting business plans to keep things running when employees are ill, while doing what they can to prevent the spread of the illness.

The Centers for Disease Control and Prevention is clear about what people should do if they have swine flu symptoms.

"If you get sick with flu-like symptoms this flu season, you should stay home and avoid contact with other people except to get medical care," according to the agency's Web site.

Integrys Energy Group is among the companies that have considered how to deal with a pandemic for a number of years, namely in the wake of an avian flu outbreak earlier this decade.

Part of that plan calls for cross-training employees to fill in for critical functions — such as payroll or safety, health and wellness — should employees fall ill, said Michele Anderson, manager of workers compensation and wellness with Integrys in Green Bay.

"While the first plan was specific to avian flu, now our plan is more generic in the event we have any pandemic," she said. "These are living, breathing documents, and they're going to change depending on what's out in the medical community."

Integrys is following guidelines set forth by the CDC and local health departments.If employees exceed their sick days or time allotted for personal matters, they can request short-term disability or time off through the Family Medical Leave Act, she said.

"Each case is being addressed individually," Anderson said. "There's no steadfast protocol in place that says if you only have five days you have to come back even if you're sick. We encourage people that have flu-like symptoms … to stay home to protect not only themselves but also other employees that may be around them."

Absenteeism hasn't yet been a problem, she said.

She echoes other area businesses in pointing out that the energy business doesn't have the luxury of shutting down if employees call in sick for a prolonged amount of time.

Source.

Monday, March 7, 2011

34 Dies; May Have Had Swine Flu

It's about swine flu cases.

A 34-year-old Bell City Council candidate who died Friday at County-USC Medical Center may have had the swine flu, also known as the H1N1 virus, it was reported today.

A brother, Jorge, told the Bell Gardens Sun that Miguel Alejandro Sanchez had been sick for about a week when he went to the hospital Friday morning and may have had the H1N1 virus.

Sanchez, a part-time teacher's aide for the Los Angeles Unified School District and a part-time Bell Parks and Recreation Department employee, had hoped to replace former City Councilman Luis Artiga, who resigned last fall amid corruption allegations, is a special election set for Tuesday.

Sanchez was part of a "Justice for Bell' slate, along with council candidates Mario Rivas and Nestor Valencia.

His cause of death has not been made public.

His brother Jorge said Sanchez was diabetic and that could have complicated his flu-like symptoms.

Source

Sunday, March 6, 2011

Residents line up for H1N1 vaccine

These article about H1N1 vaccine.

PULASKI — John and Amy Matczak of Sobieski decided Wednesday that the close proximity of the H1N1 flu vaccine clinic was worth loading up their four small children and taking the short road trip.

They were among several hundred who turned out at the Pulaski Middle School for the first of two public clinics this week sponsored by the Brown County Health Department. The second clinic is scheduled for 3 to 6 p.m. today at Shopko Hall in Ashwaubenon.

"It's their first one," Amy Matczak said, referring to her 3-year-old daughter and 2-year-old twins. "It wasn't a problem. They got the (nasal) mist."

These are the first vaccines available locally to the general public after the health officials determined that target groups — primarily pregnant women, children younger than 10 years, and those with health problems — were adequately covered and more vaccines became available.

Centers for Disease Control and Prevention officials say 85 million doses of the vaccine are now available and 10 million more are coming out every week.

Marcee Gohr, a nurse at the Pulaski Middle School, said a line began to form 45 minutes before the clinic opened at 3 p.m. Wednesday, and the traffic remained steady as people of all ages came for vaccinations in the school auditorium.

Gordon Maki of Suamico was one of them. He received a regular flu shot in September but wanted to get the H1N1 vaccination as soon as it became available.

The CDC announced Wednesday that 800,000 doses of the vaccine intended for young children are being recalled because the antigen content is below specified limits. However, the CDC said the vaccine is safe.

Judy Friederichs, director of the Brown County Health Department, said none of the doses have been sent to Green Bay.

"Parents don't need to do anything about it," Friederichs said.

Meanwhile, the state Department of Health Services reported Wednesday that four more people have died from the H1N1 flu, bringing the state death toll to 47 since April.

The new deaths were reported in the last week in Bayfield, Dane, Milwaukee and Polk counties.

The department says the number of H1N1-related hospitalizations has also increased to 854 even though the number of overall cases is declining all over the state at the moment.

Public health officials say another wave of cases could be coming, and now is a good time to get vaccinated.

Source

Saturday, March 5, 2011

Combats More Severe Flu Season With New Antibodies

Today's article about HK combats more severe flu season with new antibodies.

HONG KONG (Reuters) - Doctors hope to treat this year's severe flu epidemic in Hong Kong by harvesting antibodies from patients who have recovered, medical experts said on Tuesday.

The experts said they hoped to treat more than 70 severely ill flu patients with certain antibodies taken from patients who have recovered earlier from the H1N1 swine flu virus, now the most prevalent seasonal flu strain in Hong Kong.

Kelvin To, clinical assistant professor at the University of Hong Kong's microbiology department, told reporters that this winter had proved colder, dryer and longer than previous years and "that increases the survival of this virus and its transmission."

To and colleagues observed that patients who fell severely ill this winter developed the "cytokine effect," when the immune system goes into overdrive, killing not only the virus, but also healthy tissues.

"This chaos in the immune system led to a decrease in an important kind of antibody in the blood of these patients ... called immunoglobulin G2, which is important in our defense against many bacteria that cause secondary infection in patients with severe influenza," they wrote in a statement.

The doctors said they planned to harvest these antibodies from the blood plasma of recovered patients and use them to treat severely ill patients in the coming weeks.

"We are aiming for over 70 patients. The epidemic is ongoing, we constantly have patients enrolling into this study," To said. "We believe the concentrated antibodies will be much more effective than ordinary convalescent plasma."

This clinical trial goes a step further from an earlier Hong Kong study which found that severely ill flu patients responded well when treated with convalescent plasma.

In his comments to reporters, To said flu patients this year had a two- to fourfold decrease in antibody counts.

H1N1 has killed 10 people in Hong Kong and 51 people have undergone intensive care in public hospitals since January 24, according to a government spokeswoman -- with the median age in intensive care 51.5, lower than previous years.

The H1N1 swine flu virus makes up 90 percent of all diagnosed flu cases against 40 percent last winter.

Seasonal flu kills between 250,000 to 500,000 people each year globally and H1N1 swine flu may be slightly more deadly, but statistics will take years to gather. It affects younger adults and children more severely compared to other strains.

Source...

Friday, March 4, 2011

H1N1 Claims 3 Lives in Malaysia

Article about H1N1 claim 3 lives in Malaysia.

The A/H1N1 flu has claimed three lives this year in Malaysia, while 679 others have been tested positive for the fatal disease.

Malaysian Health Minister Liow Tiong Lai announced the figures in a statement on Thursday.

Liow warned that although it was not the peak of the flu season now, members of the public should be caution as A/H1N1 could be spread easily, particularly at schools.

A school in Malaysia was temporary closed on Wednesday after 166 students showed signs of cough and sore throat.

Liow reminded all schools to abide by the guidelines set by the ministry to prevent the disease from spreading.

The minister also urged school staff and students to seek medical treatment once they did not feel well, and stay at home until they have fully recovered.

Thursday, March 3, 2011

H1N1 and H9N2 Offspring Can Be More Lethal

Today's talks about H1N1 and H9N2 offspring can be more lethal.

Mar 2, 2011 (CIDRAP News) – Chinese researchers who tested reassortants that combined the 2009 H1N1 virus with H9N2, a subtype that commonly circulates in birds, found that several were more pathogenic then the parent viruses, which they said could pose a pandemic threat.

Their experiments also found that of 127 reassortants between the two viruses, as many as 57.5% had a high ability to replicate, similar to the two parent viruses, which suggests that the two viruses have a high genetic compatibility. The findings appeared in the Proceedings of the National Academy of Sciences. The report was edited by Dr Peter Palese, a well-known virologist at Mount Sinai School of Medicine in New York City.

Though H9N2 is a low-pathogenic virus, it has also been found in pigs, which infectious disease experts have said could be a "mixing vessel" for animal and human flu viruses, producing novel flu viruses with pandemic potential.

Human infections with H9N2 have been reported, and the World Health Organization (WHO) includes the virus alongside H5N1 in its annual recommendations for pandemic flu vaccine candidate viruses.

Unpacking virulence differences
Using reverse genetics, the study group attempted to make all possible 127 reassortants from an avian H9N2 influenza virus and the 2009 H1N1 virus. Then they categorized each into one of four groups based on replication ability.

A total of 73 reassortants showed a high ability to replicate, and the group evaluated the pathogenicity of all of them in mice. Based on those findings, they sorted the viruses into three groups that varied by how sick the mice got. Eight of the reassortants caused more severe disease, based on clinical observation such as ruffled coat, lethargy, and dyspnea, and microscopic signs in lung tissue, which included interstitial pneumonia and bronchopneumonia, edema, hemorrhage, epithelial cell dropout, and infiltration of inflammatory cells.

All eight of the most pathogenic reassortants had the polymerase acid (PA) gene segment from the 2009 H1N1 virus, which the authors suggest is required for the emergence of the most virulent reassortants they tested. Further analysis showed that the basic polymerase 1 (PB1) gene of the 2009 H1N1 virus usually attenuated the pathogenicity of the reassortants, and the neuraminidase of that parent virus typically increased their virulence.

Projecting illness impacts
Though the more virulent reassortants were a major concern, the less pathogenic ones that emerged are also worth noting, the authors state, because they could circulate undetected in mammals, and mutation or further reassortment could also pose a pandemic threat.

Not all of the reassortants that had the PA gene segment from the 2009 H1N1 virus were more virulent that their parent viruses, which the investigators said suggests that other gene segments play a role in pathogenicity.

They said their examination of the sickest mice showed no evidence of systemic spread, but all viruses replicated efficiently in the lungs and showed high polymerase activity. "These results suggested that a high virus load and high polymerase activity were important factors for the virulence of the reassortants in mice," they wrote.

The group concluded that reassortants between H9N2 and pandemic H1N1 could pose a public health threat and that the PA gene segment findings in the most virulent ones could serve as a marker for identifying H9 reassortants that present the greatest risks.

Source...

Seasonal Flu Vaccination Result in Higher Risk of Pandemic Flu Infection?

These article about seasonal flu vaccination.

Recent studies have suggested that vaccination with seasonal influenza vaccine resulted in an apparent higher risk of infection with pandemic influenza H1N1 2009. Geoffry N. Mercer, of the National Centre for Epidemiology and Population Health at Australian National University in Canberra, Australia, and colleagues, constructed a simple mathematical model incorporating strain competition and a hypothesised temporary strain-transcending immunity to investigate this observation. The model assumes that seasonal vaccine has no effect on the risk of infection with pandemic influenza.

The researchers say that results of the model over a range of reproduction numbers and effective vaccination coverage confirm this apparent increased risk in the Northern, but not the Southern, hemisphere. This is due to unvaccinated individuals being more likely to be infected with seasonal influenza (if it is circulating) and developing hypothesised temporary immunity to the pandemic strain. Because vaccinated individuals are less likely to have been infected with seasonal influenza, they are less likely to have developed the hypothesised temporary immunity and are therefore more likely to be infected with pandemic influenza. If the reproduction number for pandemic influenza is increased, as it is for children, an increase in the apparent risk of seasonal vaccination is observed. The maximum apparent risk effect is found when seasonal vaccination coverage is in the range of 20 percent to 40 percent.

Mercer, et al. conclude that only when pandemic influenza is recently preceded by seasonal influenza circulation is there a modeled increased risk of pandemic influenza infection associated with prior receipt of seasonal vaccine. Their research was published in BMC Public Health.
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